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This means Microsoft will no longer provide any security updates or other fixes for the browser after that date. I care because at work we always have to provide so many bug fixes for the browser. It is such a head ache to make things work in it. After that date businesses will be forced to update or be caught using a browser with unpatched security vulnerabilities which will cause them to fail IT audits.
Also of note is that Internet Explorer 7 will also be past its life cycle.
Reference: http://support.microsoft.com/gp/lifesupsps/#Internet_Explorer